Catalyst Development

We are interested in designing new ligand motifs to enable more effective catalysis by addressing issues such as effective asymmetric control in reactivity, more sustainable use of precious metals using lower catalyst loadings, and minimising the use of organic solvents. We have particular interest in switchable, multifunctional and adaptable ligands based on N-heterocyclic carbene (NHC) and phosphine motifs, with current projects ranging from small molecule, to supramolecular and artificial metalloenzymes. If you are interested in using our systems then do get in touch to discuss.

L-Shaped N-Heterocyclic Carbenes

AImOx motifs

A new, readily accessible, L-shaped NHC ligand motif that positions a sulfonamide adjacent to the metal centre.

A graphical abstract showing the L-shaped ligand motif and its use to make metal complex taken from Beilstein Journal of Organic Chemistry, 2024, 20, 621-627

SMART NHCs

Multifunctional ligands

We are currently working on new multifunctional L-shaped motifs and will be showing them here soon.

SMART NHCs

Artificial Metalloenzymes

In a collaboration with Dr Anna Peacock we are exploring new approaches to access novel artificial metalloenzymes and explore their potential in catalysis.

P-based ligands

P-based ligands

In a collaboration with Dr Andrew Jupp we are exploring the catalytic potential of P-based ligand motifs.